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Neo-Revascularization as the Potential Treatment for Patient Suffering from Pulmonary Arterial Hypertension (Myth or Reality)

Received: 28 April 2013     Published: 30 May 2013
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Abstract

Pulmonary arterial hypertension (APAH, IPAH) is a devastating, progressive disease with increasingly debilitating symptoms [1,2].Intrapulmonary delivery of autologous stem cells could be beneficial for pathogenetic treatment for patients with severe pulmonary arterial hypertension.Two patients with severe pulmonary artery hypertension received intrapulmonary autologous mesenchymal (mononuclear) stem cell transplantation and stem cell transplantation in pulmonary arteries. Patients were examined by scintigraphy of lungs during the periods 12, 14 and 27 months after stem cell transplantation. We find out that perfusion in all lung segments were improved after 14 and 27 months.

Published in Clinical Medicine Research (Volume 2, Issue 3)
DOI 10.11648/j.cmr.20130203.13
Page(s) 32-36
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2013. Published by Science Publishing Group

Keywords

Stem Cell Transplantation, Intrapulmonary Delivery, Pulmonary Artery Hypertension, Pulmonary Vascular Resistance

References
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Cite This Article
  • APA Style

    Aris Lacis, Inguna Lubaua, Valts Ozolins, Eriks Jekabsons, Andis Lacis, et al. (2013). Neo-Revascularization as the Potential Treatment for Patient Suffering from Pulmonary Arterial Hypertension (Myth or Reality). Clinical Medicine Research, 2(3), 32-36. https://doi.org/10.11648/j.cmr.20130203.13

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    ACS Style

    Aris Lacis; Inguna Lubaua; Valts Ozolins; Eriks Jekabsons; Andis Lacis, et al. Neo-Revascularization as the Potential Treatment for Patient Suffering from Pulmonary Arterial Hypertension (Myth or Reality). Clin. Med. Res. 2013, 2(3), 32-36. doi: 10.11648/j.cmr.20130203.13

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    AMA Style

    Aris Lacis, Inguna Lubaua, Valts Ozolins, Eriks Jekabsons, Andis Lacis, et al. Neo-Revascularization as the Potential Treatment for Patient Suffering from Pulmonary Arterial Hypertension (Myth or Reality). Clin Med Res. 2013;2(3):32-36. doi: 10.11648/j.cmr.20130203.13

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  • @article{10.11648/j.cmr.20130203.13,
      author = {Aris Lacis and Inguna Lubaua and Valts Ozolins and Eriks Jekabsons and Andis Lacis and Mara Ratniece and Andrejs Erglis},
      title = {Neo-Revascularization as the Potential Treatment for Patient Suffering from Pulmonary Arterial Hypertension (Myth or Reality)},
      journal = {Clinical Medicine Research},
      volume = {2},
      number = {3},
      pages = {32-36},
      doi = {10.11648/j.cmr.20130203.13},
      url = {https://doi.org/10.11648/j.cmr.20130203.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20130203.13},
      abstract = {Pulmonary arterial hypertension (APAH, IPAH) is a devastating, progressive disease with increasingly debilitating symptoms [1,2].Intrapulmonary delivery of autologous stem cells could be beneficial for pathogenetic treatment for patients with severe pulmonary arterial hypertension.Two patients with severe pulmonary artery hypertension received intrapulmonary autologous mesenchymal (mononuclear) stem cell transplantation and stem cell transplantation in pulmonary arteries. Patients were examined by scintigraphy of lungs during the periods 12, 14 and 27 months after stem cell transplantation. We find out that perfusion in all lung segments were improved after 14 and 27 months.},
     year = {2013}
    }
    

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  • TY  - JOUR
    T1  - Neo-Revascularization as the Potential Treatment for Patient Suffering from Pulmonary Arterial Hypertension (Myth or Reality)
    AU  - Aris Lacis
    AU  - Inguna Lubaua
    AU  - Valts Ozolins
    AU  - Eriks Jekabsons
    AU  - Andis Lacis
    AU  - Mara Ratniece
    AU  - Andrejs Erglis
    Y1  - 2013/05/30
    PY  - 2013
    N1  - https://doi.org/10.11648/j.cmr.20130203.13
    DO  - 10.11648/j.cmr.20130203.13
    T2  - Clinical Medicine Research
    JF  - Clinical Medicine Research
    JO  - Clinical Medicine Research
    SP  - 32
    EP  - 36
    PB  - Science Publishing Group
    SN  - 2326-9057
    UR  - https://doi.org/10.11648/j.cmr.20130203.13
    AB  - Pulmonary arterial hypertension (APAH, IPAH) is a devastating, progressive disease with increasingly debilitating symptoms [1,2].Intrapulmonary delivery of autologous stem cells could be beneficial for pathogenetic treatment for patients with severe pulmonary arterial hypertension.Two patients with severe pulmonary artery hypertension received intrapulmonary autologous mesenchymal (mononuclear) stem cell transplantation and stem cell transplantation in pulmonary arteries. Patients were examined by scintigraphy of lungs during the periods 12, 14 and 27 months after stem cell transplantation. We find out that perfusion in all lung segments were improved after 14 and 27 months.
    VL  - 2
    IS  - 3
    ER  - 

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Author Information
  • Clinic of Pediatric Cardiology and Cardiac Surgery, University Children Hospital, Riga, Latvia

  • Riga Stradins University, Riga, Latvia

  • Clinic of Pediatric Cardiology and Cardiac Surgery, University Children Hospital, Riga, Latvia

  • Pauls Stradins Clinical University Hospital, Riga, Latvia

  • Riga Stradins University, Riga, Latvia

  • Pauls Stradins Clinical University Hospital, Riga, Latvia

  • Latvian Institute of Cardiology, Riga, Latvia

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