| Peer-Reviewed

Selected Pharmacological Applications of 1st Row Transition Metal Complexes: A review

Received: 1 August 2017     Accepted: 7 August 2017     Published: 27 November 2017
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Abstract

Ninety elements occur naturally on earth. Out of these, nine are radioactive and among the remaining eighty one that could support life, sixty one are metals. Our bodies have approximately 3% metal. Researchers have been established that some of metal complexes were biologically active. A significantly rising interest in the design of metal complexes as drugs and diagnostic agents is currently observed in the area of scientific inquiry, specifically termed medicinal inorganic chemistry. Investigations in this area focus mostly on the speciation of metal species in biological media based on possible interactions of these metal ions with diverse biomolecules. In an effort to contribute to future development of new therapeutics or diagnostic agents metallo pharmaceuticals used as anticancer agents, anti-HIV, metal-mediated antibiotics, antibacterials, antivirals, antiparasitics, antiarthritics, antidiabetics and radio-sensitizing agents appear in therapeutic medicinal inorganic chemistry. The medicinal uses and applications of metals and metal complexes are of increasing clinical and commercial importance.

Published in Clinical Medicine Research (Volume 6, Issue 6)
DOI 10.11648/j.cmr.20170606.13
Page(s) 177-191
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Transition Metal Complexes, Antibacterial Activity, Antifungal Activity, Cytotoxicity, DNA-Interaction

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    Md. Saddam Hossain, Pijush Kanti Roy, Roushown Ali, C. M. Zakaria, Md. Kudrat-E-Zahan. (2017). Selected Pharmacological Applications of 1st Row Transition Metal Complexes: A review. Clinical Medicine Research, 6(6), 177-191. https://doi.org/10.11648/j.cmr.20170606.13

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    ACS Style

    Md. Saddam Hossain; Pijush Kanti Roy; Roushown Ali; C. M. Zakaria; Md. Kudrat-E-Zahan. Selected Pharmacological Applications of 1st Row Transition Metal Complexes: A review. Clin. Med. Res. 2017, 6(6), 177-191. doi: 10.11648/j.cmr.20170606.13

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    AMA Style

    Md. Saddam Hossain, Pijush Kanti Roy, Roushown Ali, C. M. Zakaria, Md. Kudrat-E-Zahan. Selected Pharmacological Applications of 1st Row Transition Metal Complexes: A review. Clin Med Res. 2017;6(6):177-191. doi: 10.11648/j.cmr.20170606.13

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  • @article{10.11648/j.cmr.20170606.13,
      author = {Md. Saddam Hossain and Pijush Kanti Roy and Roushown Ali and C. M. Zakaria and Md. Kudrat-E-Zahan},
      title = {Selected Pharmacological Applications of 1st Row Transition Metal Complexes: A review},
      journal = {Clinical Medicine Research},
      volume = {6},
      number = {6},
      pages = {177-191},
      doi = {10.11648/j.cmr.20170606.13},
      url = {https://doi.org/10.11648/j.cmr.20170606.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20170606.13},
      abstract = {Ninety elements occur naturally on earth. Out of these, nine are radioactive and among the remaining eighty one that could support life, sixty one are metals. Our bodies have approximately 3% metal. Researchers have been established that some of metal complexes were biologically active. A significantly rising interest in the design of metal complexes as drugs and diagnostic agents is currently observed in the area of scientific inquiry, specifically termed medicinal inorganic chemistry. Investigations in this area focus mostly on the speciation of metal species in biological media based on possible interactions of these metal ions with diverse biomolecules. In an effort to contribute to future development of new therapeutics or diagnostic agents metallo pharmaceuticals used as anticancer agents, anti-HIV, metal-mediated antibiotics, antibacterials, antivirals, antiparasitics, antiarthritics, antidiabetics and radio-sensitizing agents appear in therapeutic medicinal inorganic chemistry. The medicinal uses and applications of metals and metal complexes are of increasing clinical and commercial importance.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - Selected Pharmacological Applications of 1st Row Transition Metal Complexes: A review
    AU  - Md. Saddam Hossain
    AU  - Pijush Kanti Roy
    AU  - Roushown Ali
    AU  - C. M. Zakaria
    AU  - Md. Kudrat-E-Zahan
    Y1  - 2017/11/27
    PY  - 2017
    N1  - https://doi.org/10.11648/j.cmr.20170606.13
    DO  - 10.11648/j.cmr.20170606.13
    T2  - Clinical Medicine Research
    JF  - Clinical Medicine Research
    JO  - Clinical Medicine Research
    SP  - 177
    EP  - 191
    PB  - Science Publishing Group
    SN  - 2326-9057
    UR  - https://doi.org/10.11648/j.cmr.20170606.13
    AB  - Ninety elements occur naturally on earth. Out of these, nine are radioactive and among the remaining eighty one that could support life, sixty one are metals. Our bodies have approximately 3% metal. Researchers have been established that some of metal complexes were biologically active. A significantly rising interest in the design of metal complexes as drugs and diagnostic agents is currently observed in the area of scientific inquiry, specifically termed medicinal inorganic chemistry. Investigations in this area focus mostly on the speciation of metal species in biological media based on possible interactions of these metal ions with diverse biomolecules. In an effort to contribute to future development of new therapeutics or diagnostic agents metallo pharmaceuticals used as anticancer agents, anti-HIV, metal-mediated antibiotics, antibacterials, antivirals, antiparasitics, antiarthritics, antidiabetics and radio-sensitizing agents appear in therapeutic medicinal inorganic chemistry. The medicinal uses and applications of metals and metal complexes are of increasing clinical and commercial importance.
    VL  - 6
    IS  - 6
    ER  - 

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Author Information
  • Department of Chemistry, Rajshahi University, Rajshahi, Bangladesh

  • Department of Chemistry, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh

  • Department of Chemistry, Rajshahi University, Rajshahi, Bangladesh

  • Department of Chemistry, Rajshahi University, Rajshahi, Bangladesh

  • Department of Chemistry, Rajshahi University, Rajshahi, Bangladesh

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