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Trends and Treatment Outcomes of Tuberculosis in Debre Berhan Referral Hospital, Debre Drehan, Ethiopia

Received: 27 August 2018     Accepted: 10 September 2018     Published: 24 October 2018
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Abstract

Tuberculosis (TB) remains major Public health problem and among the top ten leading causes of human deaths worldwide. Moreover, TB is the leading cause of morbidity, one of the three major causes for hospital admission, and the second killer next to malaria in Ethiopia. Early diagnosis, effective treatment and continues assessment of treatment outcome are important to improve TB management program. Retrospective study design was conducted to assess trend and treatment outcomes of TB in Debre Berhan referral hospital. 4 years (2014 to 2017) TB case records was reviewed with standard check list and entered in to EpiData 3.1 and analyzed using SPSS version 16. Among the total registered TB patients with complete record (n=506), 256(50.6%) were males and 250(49.4%) Female. The treatment cured rate varies from 23.29% in 2006 E.C to 47.45% in 2007 E.C, whereas treatment completed varies from 46.91% in 2007 E.C to 67.08% in 2009 E.C. Majority of the smear-positive pulmonary tuberculosis patients 183 (97.3%) were cured at the end of their anti-TB treatment. The proportion of HIV co-infection among TB patients was 21.3%. However, overall cure rate was nearly the same in both HIV positive and negative patients. As conclusion majority of the smear-positive pulmonary tuberculosis patients were cured at the end of their anti-TB treatment. There was also a continuous increment of treatment success rate, indicating that the hospital is within the track of WHO target currently. However the proportion of HIV co-infection among TB patients was higher which signifies the urgent need for staff capacity building and increasing public awareness.

Published in Clinical Medicine Research (Volume 7, Issue 5)
DOI 10.11648/j.cmr.20180705.11
Page(s) 97-102
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

Trends, Treatment Outcomes, Tuberculosis

References
[1] World Health Organization, Global Tuberculosis Control: WHO Report 2015, WHO/HTM/TB/ 2015. 22, World Health Organization, Geneva, Switzerland, 2015.
[2] World Health Organization, Global Tuberculosis Control report: WHO Report 2014, WHO/HTM/TB/ 2014. 08, World Health Organization, Geneva, Switzerland, 2014.
[3] World Health Organization, Global Tuberculosis Control: WHO Report 2011, WHO/HTM/TB/ 2011.16, World Health Organization, Geneva, Switzerland, 2011.
[4] Federal Democratic Republic of Ethiopia, Ministry of Health (FMOH) (2009) TB/ HIV implementation guideline, Addis Ababa, Ethiopia.
[5] Ai X, Men K, Guo L et al., Factors associated with low cure rate of tuberculosis in remote poor areas of Shaanxi Province, China: a case control study, BMC Public Health, 2010 vol. 10, article 112.
[6] Berhe G, Enquselassie F, and Aseffa A, Treatment outcome of smear-positive pulmonary tuberculosis patients in Tigray Region, Northern Ethiopia, BMC Public Health, 2012, vol. 12, p. 537.
[7] Demeke D, Legesse M, Bati J. Trend of Tuberculosis and Treatment Outcomes in Gambella Region with Special Emphasize on Gambella Regional Hospital, Western Ethiopia. J Mycobac Dis, 2013, 3: 130.
[8] Nigatu T, Abraha M (2010) Epidemiological analysis of tuberculosis trends in Ethiopia Tüberküloz, 2010; 58: 375-384.
[9] World Health Organization: Global Plan to Stop TB 2011-2015. Davos, Switzerland: WHO; 2006.
[10] Tessema B, Muche A, Bekele A, Reissig D, Emmrich F, and Sack U. Treatment outcome of tuberculosis patients at Gondar University Teaching Hospital, Northwest Ethiopia. A five year retrospective study, BMC Public Health, 2009; vol. 9, article 371.
[11] Biadglegne F, Anagaw B, Debebe T et al., A retrospective study on the outcomes of tuberculosis treatment in Felege Hiwot Referral Hospital, Northwest Ethiopia, International Journal of Medical Sciences, 2013; vol. 5, no. 2, pp. 85–91.
[12] Ramos JM, Reyes F, and Tesfamariam A, Childhood and adult tuberculosis in a rural hospital in Southeast Ethiopia: a ten-year retrospective study, BMC Public Health, 2010; vol. 10, article 215.
[13] World Health Organization, G Global Tuberculosis Report 2012, WHO, Geneva, Switzerland, 2012.
[14] Sisay S, Mengistu B, Erku W, WoldeyohannesD. Directly Observed Treatment Short-course (DOTS) for tuberculosis control program in Gambella Regional State, Ethiopia: ten years’ experience. BMC Res Notes, 2014;7(44):1756-0500.
[15] Belete G, Gobena A, Girmay M, Sibhatu B. Treatment outcome of tuberculosis patients under directly observed treatment in Addis Ababa, Ethiopia. Braz J Infect Dis, 2013;17(5):521-528.
[16] Belay T, Abebe M, Assegedech B, Dieter R, Frank E, Ulrich S. Treatment outcome of tuberculosis patients at Gondar University Teaching Hospital, Northwest Ethiopia: Afive-year retrospective study. BMC Public Health, 2009; 9(371):1471-2458.
[17] Ukwaja KN, Modebe O, Igwenyi C, Alobu I. The economic burden of tuberculosis care for patients and households in Africa: a systematic review. The International Journal of Tuberculosis and Lung Disease, 2012; 16(6); 733-739.
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  • APA Style

    Tsegahun Asfaw, Moges Lewetegn, Helen Tariku. (2018). Trends and Treatment Outcomes of Tuberculosis in Debre Berhan Referral Hospital, Debre Drehan, Ethiopia. Clinical Medicine Research, 7(5), 97-102. https://doi.org/10.11648/j.cmr.20180705.11

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    ACS Style

    Tsegahun Asfaw; Moges Lewetegn; Helen Tariku. Trends and Treatment Outcomes of Tuberculosis in Debre Berhan Referral Hospital, Debre Drehan, Ethiopia. Clin. Med. Res. 2018, 7(5), 97-102. doi: 10.11648/j.cmr.20180705.11

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    AMA Style

    Tsegahun Asfaw, Moges Lewetegn, Helen Tariku. Trends and Treatment Outcomes of Tuberculosis in Debre Berhan Referral Hospital, Debre Drehan, Ethiopia. Clin Med Res. 2018;7(5):97-102. doi: 10.11648/j.cmr.20180705.11

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  • @article{10.11648/j.cmr.20180705.11,
      author = {Tsegahun Asfaw and Moges Lewetegn and Helen Tariku},
      title = {Trends and Treatment Outcomes of Tuberculosis in Debre Berhan Referral Hospital, Debre Drehan, Ethiopia},
      journal = {Clinical Medicine Research},
      volume = {7},
      number = {5},
      pages = {97-102},
      doi = {10.11648/j.cmr.20180705.11},
      url = {https://doi.org/10.11648/j.cmr.20180705.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20180705.11},
      abstract = {Tuberculosis (TB) remains major Public health problem and among the top ten leading causes of human deaths worldwide. Moreover, TB is the leading cause of morbidity, one of the three major causes for hospital admission, and the second killer next to malaria in Ethiopia. Early diagnosis, effective treatment and continues assessment of treatment outcome are important to improve TB management program. Retrospective study design was conducted to assess trend and treatment outcomes of TB in Debre Berhan referral hospital. 4 years (2014 to 2017) TB case records was reviewed with standard check list and entered in to EpiData 3.1 and analyzed using SPSS version 16. Among the total registered TB patients with complete record (n=506), 256(50.6%) were males and 250(49.4%) Female. The treatment cured rate varies from 23.29% in 2006 E.C to 47.45% in 2007 E.C, whereas treatment completed varies from 46.91% in 2007 E.C to 67.08% in 2009 E.C. Majority of the smear-positive pulmonary tuberculosis patients 183 (97.3%) were cured at the end of their anti-TB treatment. The proportion of HIV co-infection among TB patients was 21.3%. However, overall cure rate was nearly the same in both HIV positive and negative patients. As conclusion majority of the smear-positive pulmonary tuberculosis patients were cured at the end of their anti-TB treatment. There was also a continuous increment of treatment success rate, indicating that the hospital is within the track of WHO target currently. However the proportion of HIV co-infection among TB patients was higher which signifies the urgent need for staff capacity building and increasing public awareness.},
     year = {2018}
    }
    

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    AU  - Tsegahun Asfaw
    AU  - Moges Lewetegn
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    AB  - Tuberculosis (TB) remains major Public health problem and among the top ten leading causes of human deaths worldwide. Moreover, TB is the leading cause of morbidity, one of the three major causes for hospital admission, and the second killer next to malaria in Ethiopia. Early diagnosis, effective treatment and continues assessment of treatment outcome are important to improve TB management program. Retrospective study design was conducted to assess trend and treatment outcomes of TB in Debre Berhan referral hospital. 4 years (2014 to 2017) TB case records was reviewed with standard check list and entered in to EpiData 3.1 and analyzed using SPSS version 16. Among the total registered TB patients with complete record (n=506), 256(50.6%) were males and 250(49.4%) Female. The treatment cured rate varies from 23.29% in 2006 E.C to 47.45% in 2007 E.C, whereas treatment completed varies from 46.91% in 2007 E.C to 67.08% in 2009 E.C. Majority of the smear-positive pulmonary tuberculosis patients 183 (97.3%) were cured at the end of their anti-TB treatment. The proportion of HIV co-infection among TB patients was 21.3%. However, overall cure rate was nearly the same in both HIV positive and negative patients. As conclusion majority of the smear-positive pulmonary tuberculosis patients were cured at the end of their anti-TB treatment. There was also a continuous increment of treatment success rate, indicating that the hospital is within the track of WHO target currently. However the proportion of HIV co-infection among TB patients was higher which signifies the urgent need for staff capacity building and increasing public awareness.
    VL  - 7
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Author Information
  • Department of Medical Laboratory Science, Debre Berhan University, Debre Berhan, Ethiopia

  • Department of Medical Laboratory Science, Debre Berhan University, Debre Berhan, Ethiopia

  • Department of Medical Laboratory Science, Debre Berhan University, Debre Berhan, Ethiopia

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